T-Sense project is dedicated to promote scientific excellence by developing a novel optical fiber sensor (OFS) technology for monitoring the dose delivered to patients receiving radiation therapy used to cure prostate cancer. The main goal of the project is to advance the current state-of-the-art in optical fiber sensors by investigating and developing novel sensors capable for real-time, in-vivo radiation dose and hypoxia measurements in prostate cancer treatment.
This will be achieved through the implementation of the following scientific and technological research objectives:
Investigate, develop, characterize and technically validate OFSs for radiation dosimetry with high sensitivity, centigray (cGy) resolution, linearity and accuracy, for the range of radiation activity used in brachytherapy.
Investigate, develop, characterise and technically validate OFSs for tumor oxygenation level monitoring with high sensitivity, linearity and accuracy.
Theoretically analyze and model the behavior of the sensors, thereby establishing fundamental design criteria for optimized sensor performance.
Deliver a demonstrator application, e.g. rectal wall monitoring during prostate cancer treatment.
Explore areas of OFSs for oncology, e.g. optical fiber based calorimetry sensors for external beam radiotherapy, distributed dose monitoring, and targeted drug delivery and phototherapy.
“The Project EXCELLENCE/0918/0324 is co-financed by the European Regional Development Fund and the Republic of Cyprus through the Research and Innovation Foundation”